Neuroscience clinical trials

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Neuroscience clinical trials

Central Nervous Systems (CNS) trials are inherently complex. Unlike many other therapeutic areas, neuroscience trials rely heavily on subjective endpoints and human judgment. Among the numerous challenges, endpoint subjectivity, the complexity and heterogeneity of patient populations, and data accuracy and variability are frequently cited.
To mitigate these challenges, designing effective Rater Training programs and combining them with flexible and user friendly eCOA solution is the only option to derisk your neuroscience clinical trials data and enhance the chances of clinical trials success.

At Kayentis, we have the experience and expertise to tackle the challenges of your CNS trials. Our partnership with RWS helps improve consistency across sites, strengthen endpoint reliability, and support inspection-ready datasets.

Kayentis eCOA solution is designed to address CNS-specific requirements

Adaptable to real-world site conditions and designed for complex ClinRO administration

Standardized digital instruments, automated scoring, and guided workflows to reduce subjectivity, resulting in improved reliability and reduced variability
Frequent real-time data capture, reduced recall bias, time-stamped entries, automated reminders, relevant branching logic and compliance tracking for stronger data collection and higher data quality
Integrated access controls, ensuring only certified clinicians can complete specific assessments, reducing the risk of unqualified or out-of-date raters
Multiple data entry modalities, enhancing flexibility and better matching the day-to-day life of patients, caregivers and clinicians

We have extensive experience across many indications, including Parkinson’s disease, Alzheimer’s disease, neuropathies, ataxia, and DMD, and with multiple scales, including C-SSRS, ADAS-Cog14, CDR-SB, and CDAS.

Guillaume Juge

CEO at Kayentis

“Capturing data digitally isn’t enough, sponsors need data they can trust. By aligning rater qualification with purpose-built eCOA workflows, we help reduce variability and give teams greater confidence in their results. This partnership with RWS brings a more coordinated approach, aligning how clinicians are trained, certified and monitored with how data is captured and controlled.”

Highly expert Rater training services

Together with RWS, we offer a fully integrated solution combining eCOA technology and rater training services to ensure clinicians involved in patient assessments are properly qualified, consistently trained, and monitored throughout the trial lifecycle.

Training Research & Development, translation & facilitation
Raters qualification management
Learning Management System (LMS) hosting & management
Certification
Monitoring & retraining
Site coordination and operational oversight

Built to fit your ecosystem

While we partner specifically with RWS, we can connect with:

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