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Data Collection in Clinical Trials with Multiple Caregivers

Last updated: May 30, 2025

In clinical trials, especially those involving participants unable to self-report—such as children or individuals with cognitive impairments—caregiver-reported data is essential. However, when multiple caregivers are involved, challenges like inter-rater variability and missing data arise.

Should data collection be limited to a single caregiver, potentially leading to more missing data, or involve multiple caregivers, providing more complete data but with greater variability?

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