Therapeutic areas

While the integration of Patient-Reported Outcomes (PROs) into phase IIb and III clinical trials has become increasingly widespread in the...

Article

Patient-Reported Outcomes in early-phase oncology clinical trials
A Stepping Stone to a Patient-Centered Drug Development

Oncology Patient engagement

In phase I clinical trials, the recommended phase II dose (RP2D) is usually set at or near the maximum tolerated...

White Paper

Gastrointestinal Tract Diseases Research: Moving Towards Patient-Centered Clinical Trials

Gastroenterology

The management of gastrointestinal tract diseases, especially inflammatory bowel disease (IBD), has been transformed over the past few decades. This...

Article

Turning experience into evidence: PROs in IBD clinical research

Gastroenterology

Inflammatory Bowel Disease (IBD), including Crohn’s disease or Ulcerative Colitis, presents a complex and highly individualized clinical picture, making it...

Article

If Patients Want A Better Quality Of Life, Why Isn’t That A Focus For Pharma?

A conversation with Frédéric Fiteni, Ph.D., medical oncologist and oncology PRO specialist, University Hospital of Nîmes, and, member of Kayentis Scientific...

Case study

Immunology Case Study

Immuno-Inflammation

Immunology studies present specific challenges: their eCOA build can be complex, site staff must play a key role, and study...

Article

The unquestionable value of electronic Clinical Outcome Assessments (eCOA) in rheumatoid arthritis clinical research

Immuno-Inflammation

Rheumatoid Arthritis (RA) is a common, chronic disease that causes inflammation and often presents with pain in the joints. Untreated,...

Article

Collecting PRO data in leukemia clinical research: the only way to meaningfully improve patients’ quality of life

The prevalence of leukemia is increasing worldwide. Chronic Myeloid Leukemia (CML) patients benefit from recently improved care but receive prolonged,...

Article

Collecting PRO data in cancer trials: bringing the patient perspective in oncology clinical research

As one of the biggest research area, oncology remains the focus of the clinical trials pipeline, comprising 44% of the...

Article

Rare disease clinical research: it is time to tackle what matters most to patients

Rare disease

Supporting the development and evaluation of new treatments for rare diseases has become a key priority of the 21st century....

Podcast

Rethinking pediatric clinical trials: guidelines from pediatric experts

In this last episode on pediatric clinical trial challenges, Begoña Nafria, pediatrician and patient engagement lead at SJD Barcelona Children’s...

Podcast

Overcoming challenges in long-lasting pediatric clinical trials – Insights from site experts

Metabolic Scientific advice

In this third episode on pediatric clinical trial challenges, Begoña Nafria, pediatrician and patient engagement lead at SJD Barcelona Children’s...

Case study

Tackling the specificities of NASH/MASH clinical trials

Metabolic

Integrating PROs into studies on MASH, also known as NASH, is crucial. MASH is a debilitating chronic illness that significantly impairs...

Case study

Mastering pediatric asthma clinical trials

Pediatric Respiratory

Asthma clinical trials present several specificities, such as the use of disease-specific health-related quality of life instruments. Asthma clinical research...

Article

The importance of ePRO to support NASH/NAFLD unmet clinical research and medical needs

NonAlcoholic SteatoHepatitis (NASH), now called Metabolic Dysfunction-Associated SteatoHepatitis (MASH), affects almost 115 million adults globally and is the most severe...

Podcast

How DCTs Can Help Pediatric Clinical Research – Insights From Site Experts

In this second episode on pediatric clinical trial challenges, Begoña Nafria, pediatrician and patient engagement lead at SJD Barcelona Children’s...

Case study

Ophthalmology Clinical Trials

Ophthalmic conditions and vision impairment currently affect 2.2 billion people globally: Data collection can be very challenging for patients with...

White Paper

Innovation and Partnerships: The Biotech Perspective

biotech Cardiology

In the ever-evolving landscape of biotechnology, groundbreaking advancements continue to shape the future of healthcare. In this exclusive interview, Estelle...

Podcast

Exploring The Specific Challenges Of Pediatric Clinical Trials – Insights From Site Experts

Patients insights Rare disease

In this first episode on pediatric clinical trial challenges, Begoña Nafria, pediatrician and patient engagement lead at SJD Barcelona Children’s...

Article

Implementing electronic Patient Reported Outcomes (ePROs) in Arthritis Clinical Research: Importance, benefits, and management for incorporating ePROs

Immuno-Inflammation

Arthritis is a general term categorized by acute or chronic inflammation of the joints. Arthritis may cause a variety of...

Webcast

Working with patient associations: What is the key to a positive interaction?

What rare disease patients and families want is a simpler life.Discover here what makes the relationship between the members of...

Webcast

How a patient association gave rise to a company

Patients insights Rare disease

A patient association in rare diseases is first and foremost families who all have one thing in common: they need...

Article

Direct insights from cancer patients: How they help us understand disease burden and the need for an individualized approach

Oncology Patients insights

Cultural differences and individual preferences have a significant impact on healthcare and clinical trial experience. Solutions exist in attempt to...

Case study

Rare Disease case study

Rare disease

Over 90% of rare diseases have no treatment… There are more than 6,000 known rare diseases... Approximately 80% of them have...

Case study

Tackling the complexity of pediatric clinical trials

Despite the evolution in pediatric legislation and a renewed interest in developing therapeutics for pediatric and rare diseases, pediatric clinical...

Case study

Kayentis & RWS partnering for success

Project management

Kayentis (global provider of eCOA and DCT solutions) and RWS (language service provider (LSP) and linguistic validation experts) were selected...

Article

Mitigating the risks of long-term oncology eCOA clinical trials

Long study duration can have a negative impact on patient complianceAs for any clinical trial, poor compliance in oncology studies...

Infographic

Customizing eCOA questionnaire design to improve the pediatric experience

Dedicated to improve patient experience in clinical trials, Kayentis’ Clin’form solution offers the flexibility to customize questionnaire design with illustrations...

Article

Addressing the specific complexities of oncology eCOA clinical trials

The oncology research pathway is paved with numerous challenges, and oncology clinical trials have one of the lowest success rates....

Case study

Oncology Case Study

Oncology studies present specific challenges that generate complex eCOA build and management: complex study design, frequent amendments, and long study...

Case study

Dermatology Case Study

Dermatology

Kayentis offers extensive expertise in dermatology and a solid experience with several typical PROs, ClinROs and Patient Diaries.With a large...

Digitalization Trends in Tackling the Complexity of Clinical Trials for Patients with Multiple Health Conditions

Rare disease

Patients participating in clinical research face a whole range of challenges, and it is particularly worse for those living with...

Article

eCOA solutions in oncology: how to avoid common pitfalls and ensure the success of long-term studies?

Oncology Project management

Among numerous clinical study procedures, capturing patients reported outcomes can bring its own set of challenges and, if not well...

White Paper

eCOA challenges of long term studies

How to anticipate eCOA complexities in multi-year studies & develop best practice to support sites? Using eCOA solutions can bring...

Article

eCOA in ophthalmology: The five keys for successful ePRO selection in your ophthalmology clinical trial

There is an extended use of Patient Reported Outcome (PRO) measures in clinical trials used to assess health-related quality of...

eCOA in ophthalmology

There is an extended use of Patient Reported Outcome (PRO) measures in clinical trials used to assess health-related quality of...

Infographic

Infography: Overcoming complexities in pediatric clinical studies

Approximately one in every five pediatric clinical study fail1,2 . A 2016 study shows that over a three-year period (2008 -2011),...

Key #5 for successful ePRO selection in your ophthalmology clinical trial: Anticipate cultural differences in multi country clinical trials

https://youtu.be/-dWvQaRUwYs Before selecting a PRO for use in a large global trial, it is important to anticipate that responses to...

Case study

Kayentis supports the 1st personalized immunotherapy treatment approved by both FDA & EMA

Acute Lymphoblastic or Lymphoid Leukemia (ALL) is a cancer of the lymphocytes that can result in serious complications such as...

3 reasons for using tablet for clinical data collection @Home

Electronic capture of patient data is increasingly replacing the use of paper-based diaries, and electronic Clinical Outcomes Assessment (eCOA) tools...

Article

Overcoming the Complexities of Pediatric Clinical Trials

Although children make up 25% of the world’s population, at least 50% of all drug products may still lack labeling...

Key #4 for successful ePRO selection in your ophthalmology clinical trial: Consider the method of ePRO administration

https://youtu.be/cY5lYM_wBDQ PROs in ophthalmology trials can either be self-administered by the patient or the responses can be collected through an...

Key #3 for successful ePRO selection in your ophthalmology clinical trial: Get your patients involved

https://youtu.be/Cp7vd1fBKbc Although clinical research stakeholders strive to be patient-centered in their approach, dependence on clinical parameters alone is not enough....

Key #2 for successful ePRO selection in your ophthalmology clinical trial: Use your PROs to power economic evaluations

https://youtu.be/rH4yG-sxE9w Incorporating an economic evaluation within a trial provides valuable information for clinical decision making and coverage determinations, particularly when...

Infographic

Key #1 for successful ePRO selection in your ophthalmology clinical trial: Ensure the ePRO answers the intended clinical endpoint